S-23 Powder

A. Introduction

S-23 is recognized in the scientific community as one of the most potent SARMs currently available for laboratory study. Originally developed to investigate potential applications in hormonal therapy and male contraception, it serves as a critical reference standard for laboratories exploring the tissue-selective activation of androgen receptors.

B. Scientific Overview

Chemically identified as (S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide ($C_{18}H_{13}ClF_{4}N_{2}O_{3}$), S-23 is a substituted propanamide. In research settings, it is utilized to study the suppression of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) through negative feedback loops. Researchers focus on its high binding affinity ($K_i$ of ~0.5 nM) and its ability to promote anabolic gene expression while maintaining high selectivity.

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C. Product Specifications

• Form: Crystalline powder

• Chemical Class: Substituted Propanamide / SARM

• Molecular Formula: $C_{18}H_{13}ClF_{4}N_{2}O_{3}$

• Molecular Weight: 416.75 g/mol

• Purity: ≥99% (HPLC/NMR Verified)

• Solubility: Soluble in DMSO (up to 20 mg/mL) and Ethanol

• Storage: Store at room temperature (15°C to 25°C) in a dry, airtight container protected from light and moisture.

D. Laboratory Use Context

S-23 powder is provided exclusively for in-vitro research and analytical testing. It is a primary reagent for:

• Investigating tissue-selective androgen receptor modulation in cell cultures.

• Studying the molecular mechanisms of gonadotropin suppression.

• Calibration and validation of LC-MS and GC-MS equipment for SARM screening.

• In-vitro comparative analysis of halogenated SARM analogues.

E. Quality & Testing

• HPLC Verification: Every batch is rigorously tested to confirm ≥99% chemical purity and molecular consistency.

• Structural Identity: Mass Spectrometry (MS) and Proton NMR verify the presence of the trifluoromethyl, cyano, and halogenated phenoxy groups.

• Batch Consistency: Manufactured under strict laboratory protocols to ensure reproducible results for complex longitudinal studies.

• COA: Comprehensive Certificates of Analysis are available for all institutional research requirements.

F. Shipping & Handling

Our S-23 powder is dispatched in professional, moisture-proof, and UV-protected packaging to maintain chemical integrity during transit. We provide reliable, discreet worldwide shipping to support the requirements of international research facilities and commercial laboratories.

G. Compliance Disclaimer (CLEAR & PROMINENT)

FOR RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION. This product is a research chemical and is strictly intended for in-vitro laboratory applications and analytical testing. It is not intended for diagnostic or therapeutic use in humans or animals. No medical instructions or dosages are provided. The purchaser is solely responsible for compliance with all local and international laws regarding the acquisition and handling of this substance.