RAD-140 powder (Testolone)

A. Introduction

RAD-140 (Testolone) is one of the most widely studied compounds in the SARM category. Developed to overcome the limitations of traditional anabolic steroids, it is utilized by research institutions to investigate selective activation of androgen receptors in bone and muscle tissues while minimizing activity in androgenic organs.

B. Scientific Overview

Chemically identified as 2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methylbenzonitrile ($C_{20}H_{16}ClN_{5}O_{2}$), RAD-140 is a substituted benzonitrile. In research settings, it is utilized to study the molecular mechanisms of protein synthesis and its potential neuroprotective effects against excitotoxic insults. Its high affinity for the androgen receptor ($K_i$ of ~7 nM) makes it a primary focal point for Structure-Activity Relationship (SAR) mapping.

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C. Product Specifications

• Form: Crystalline powder

• Chemical Class: Substituted Benzonitrile / SARM

• Molecular Formula: $C_{20}H_{16}ClN_{5}O_{2}$

• Molecular Weight: 393.83 g/mol

• Purity: ≥99% (HPLC/NMR Verified)

• Solubility: Soluble in DMSO (up to 30 mg/mL) and Ethanol

• Storage: Store at room temperature (15°C to 25°C) in a dry, airtight container protected from light and moisture.

D. Laboratory Use Context

RAD-140 powder is provided exclusively for in-vitro research and analytical testing. It is a primary reagent for:

• Investigating tissue-selective androgen receptor modulation in cell cultures.

• Studying the molecular pathways of osteoblast and myoblast differentiation.

• Calibration and validation of LC-MS and GC-MS equipment for SARM screening.

• In-vitro toxicity and stability profiling in synthetic biological matrices.

E. Quality & Testing

• HPLC Verification: Every batch is rigorously tested to confirm ≥99% chemical purity and the absence of related synthesis precursors.

• Structural Identity: Mass Spectrometry (MS) and Proton NMR verify the presence of the oxadiazol and benzonitrile structural components.

• Batch Consistency: Manufactured under strict laboratory protocols to ensure reproducible results for complex longitudinal studies.

• COA: Comprehensive Certificates of Analysis are available for all institutional research requirements.

F. Shipping & Handling

Our RAD-140 powder is dispatched in professional, moisture-proof, and UV-protected packaging to maintain chemical integrity during transit. We provide reliable, discreet worldwide shipping to support the requirements of international research facilities and commercial laboratories.

G. Compliance Disclaimer (CLEAR & PROMINENT)

FOR RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION. This product is a research chemical and is strictly intended for in-vitro laboratory applications and analytical testing. It is not intended for diagnostic or therapeutic use in humans or animals. No medical instructions or dosages are provided. The purchaser is solely responsible for compliance with all local and international laws regarding the acquisition and handling of this substance.