GW-501516 Powder

A. Introduction

GW-501516 (Cardarine) is a well-characterized metabolic research chemical that functions as a selective ligand for the PPARδ receptor. In scientific literature, it is a primary tool for investigating the regulation of lipid metabolism, glucose homeostasis, and mitochondrial biogenesis. Our GW-501516 powder is processed to ensure maximum solubility and stability for various in-vitro experimental designs.

B. Scientific Overview

Chemically identified as 2-(4-((2-(4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methylthio)-2-methylphenoxy)acetic acid ($C_{21}H_{18}F_{3}NO_{3}S_{2}$), Cardarine is a non-hormonal compound. Research focus typically involves its ability to activate the expression of genes associated with fatty acid oxidation (such as CPT1) and oxidative phosphorylation. Because it bypasses androgenic pathways, it is a critical control in studies differentiating between SARM-mediated and PPAR-mediated cellular responses.

C. Product Specifications

• Form: Crystalline powder

• Chemical Class: PPARδ Agonist / Thiazole derivative

• Molecular Formula: $C_{21}H_{18}F_{3}NO_{3}S_{2}$

• Molecular Weight: 453.5 g/mol

• Purity: ≥99% (HPLC/NMR Verified)

• Solubility: Soluble in DMSO (up to 20 mg/mL) and Ethanol (up to 5 mg/mL)

• Storage: Store at room temperature (15°C to 25°C) in an airtight container; long-term storage in a cool, dry environment is recommended.

D. Laboratory Use Context

This pure powder format is provided exclusively for in-vitro research and analytical testing. It is an ideal reagent for:

• Investigating PPARδ-mediated gene transcription in cell cultures.

• Calibrating LC-MS and GC-MS equipment for metabolic modulator screening.

• Studying the molecular mechanisms of energy expenditure in skeletal muscle cells.

• Developing internal laboratory standards for toxicological profiling.

E. Quality & Testing

• HPLC Verification: Each batch is tested to confirm chemical purity and the absence of heavy metal contaminants.

• Structural Identity: Mass Spectrometry (MS) and Proton NMR ensure the correct trifluoromethyl-thiazole structure.

• Traceability: Every sample is assigned a batch number, ensuring full accountability for longitudinal research projects.

• COA: Comprehensive Certificates of Analysis are available for all verified institutional purchasers.

F. Shipping & Handling

Our GW-501516 powder is dispatched in double-sealed, light-protected, and moisture-proof packaging to prevent chemical degradation during transit. We provide professional, discreet worldwide shipping to support the logistical needs of international research facilities and commercial laboratories.

G. Compliance Disclaimer (CLEAR & PROMINENT)

FOR RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION. This product is a research chemical and is strictly for in-vitro laboratory applications and analytical testing. It is not intended for diagnostic or therapeutic use in humans or animals. No instructions for administration or medical dosages are provided. The purchaser assumes all responsibility for compliance with local and international regulations regarding the acquisition and handling of this substance.