Pagoclone Pellets – 10mg

A. Introduction

Pagoclone Pellets – 10mg are a premium laboratory‑grade cyclopyrrolone research compound delivered in compact pressed‑pellet format, with each unit containing 10mg of pagoclone. This standardized pellet form provides researchers with a consistent, contamination‑minimized material optimized for controlled, non‑clinical experiments involving GABAA‑targeted ligands and related anxiolytic‑class reference substances. The product is supplied strictly for analytical and research‑oriented workflows and is not intended for any human or animal‑facing application.

B. Scientific Overview

Pagoclone (CAS 133737‑32‑3, synonyms CI‑1043, IP‑456, RP‑59037, RP‑62955) is a nonbenzodiazepine cyclopyrrolone‑derived ligand that interacts with the benzodiazepine site on GABAA receptors and functions as a partial agonist at α1‑, α2‑, α3‑, and α5‑containing subtypes. Within the scientific literature, this class of compounds is typically characterized for its receptor‑binding profile, subtype‑selectivity parameters, and broader physicochemical and chromatographic behavior under strictly controlled, in‑vitro research conditions, with no reference to human‑experience‑oriented data. Pagoclone Pellets – 10mg are supplied as a laboratory‑grade cyclopyrrolone reference material and must not be used for diagnostic, therapeutic, or consumer‑oriented purposes.

C. Product Specifications

• Product Name: Pagoclone Pellets – 10mg

• Chemical Name: Pagoclone (common non‑proprietary designation; formally 2‑(7‑chloro‑1,8‑naphthyridin‑2‑yl)‑3‑(5‑methyl‑2‑oxohexyl)isoindolin‑1‑one in common research‑supply variants)

• Synonyms: CI‑1043, IP‑456, RP‑59037, RP‑62955

• CAS Number: 133737‑32‑3 (or 133737‑48‑1, depending on supplier and salt form)

• Molecular Formula: C₂₃H₂₂ClN₃O₂ (or closely related naphthyridine‑linked isoindolinone variants)

• Molecular Weight: Approximately 407.9–426.9 g/mol, depending on the specific isomer and salt form

• Form: Solid pressed pellets

• Dosage per Unit: 10mg per pellet (labeled amount)

• Purity: Typically ≥ 98–99% research‑grade, where verified by analytical methods such as HPLC, LC‑MS, or NMR

• Appearance: Uniform, off‑white to lightly tinted compact pellets

• Solubility: Generally soluble in common organic solvents such as ethanol, methanol, DMSO, and acetonitrile, supporting controlled extraction into solution for chromatographic or receptor‑binding studies

• Storage Conditions: Store in a cool, dry, light‑resistant, low‑humidity environment inside sealed, moisture‑resistant, and light‑blocking packaging; refrigeration at 2–8°C is recommended to help preserve chemical stability and minimize degradation over time

D. Laboratory Use Context

Pagoclone Pellets – 10mg are positioned exclusively for in‑vitro, analytical, and non‑clinical research, including chromatographic profiling of cyclopyrrolone‑class ligands, method development for detection in complex matrices, receptor‑binding studies at GABAA‑linked benzodiazepine sites, and physicochemical stability testing under controlled laboratory conditions. The pellet format supports reproducible mass loading, clean extraction into standardized solvents, and precise calibration‑curve construction, making it particularly useful for laboratories focused on reference‑standard work, forensic toxicology, or pharmacological screening of nonbenzodiazepine‑type GABAA modulators. This product must not be used in any human or animal‑focused therapeutic, preventive, or diagnostic context and is reserved for lawful, laboratory‑based research by qualified personnel.

E. Quality & Testing

Every batch of Pagoclone Pellets – 10mg undergoes rigorous quality assurance:

• Third‑party Certificate of Analysis (COA) available upon request, including chromatographic data, purity estimates, and retention‑time values

• Batch‑specific tracking and full documentation for traceability to support regulated laboratory workflows and ICH‑aligned practices

• Independent laboratory verification of identity and purity for pagoclone and related impurities, with degradation or process‑related by‑products typically kept below established thresholds

• Manufactured under controlled, ISO‑aligned conditions to ensure consistent pellet mass, mechanical integrity, and suitability for receptor‑binding assays, calibration, and method‑validation studies

F. Shipping & Handling

We provide discreet, professional shipping worldwide to qualified research institutions and laboratories. Orders are securely packaged in neutral, light‑resistant, and moisture‑resistant, often foil‑or pouch‑sealed materials to help maintain the integrity of the cyclopyrrolone pellets during transit. Tracking information is supplied with every shipment, and packaging is designed to minimize exposure to heat, humidity, and physical shocks. Researchers are responsible for verifying the legality of importation and handling in their jurisdiction prior to ordering, including compliance with local regulations governing psychoactive and GABAA‑modulating research compounds.

G. Compliance Disclaimer

For Research Use Only. Not for human consumption.
This product is sold strictly for laboratory and analytical research purposes. It is not intended for human or veterinary use, ingestion, or any form of consumption. No claims are made regarding effects on biological systems outside of controlled in‑vitro research settings.

Buyers must be qualified researchers or institutions and agree to comply with all local, state, federal, and international regulations governing cyclopyrrolone‑class ligands and GABAA‑targeting research chemicals. The seller assumes no liability for misuse. Always consult your institution’s safety and compliance guidelines before receiving, storing, or handling Pagoclone Pellets – 10mg.